Michael J Shattock Selected Research

Ischemia

1/2020	The Amplitude-Normalized Area of a Bipolar Electrogram as a Measure of Local Conduction Delay in the Heart.
1/2019	Ablation of Toll-like receptor 9 attenuates myocardial ischemia/reperfusion injury in mice.
10/2006	Cardioprotection initiated by reactive oxygen species is dependent on activation of PKCepsilon.
10/2005	Antimycin A induced cardioprotection is dependent on pre-ischemic p38-MAPK activation but independent of MKK3.
7/2005	Ischemic preconditioning: a potential role for protein S-thiolation?
1/2004	Ischemia-induced phosphorylation of phospholemman directly activates rat cardiac Na/K-ATPase.
8/2003	Reversible cysteine-targeted oxidation of proteins during renal oxidative stress.
3/2003	Cardiac ischemia causes inhibition of the Na/K ATPase by a labile cytosolic compound whose production is linked to oxidant stress.
11/2002	Glyceraldehyde phosphate dehydrogenase oxidation during cardiac ischemia and reperfusion.
3/2002	Detection, quantitation, purification, and identification of cardiac proteins S-thiolated during ischemia and reperfusion.

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Michael J Shattock Research Topics

Disease

10	Ischemia 01/2020 - 03/2002
5	Infarction (Infarctions) 01/2019 - 10/2005
4	Heart Failure 10/2023 - 01/2018
4	Myocardial Infarction 11/2022 - 05/2004
4	Reperfusion Injury 11/2022 - 09/2010
3	Hypertension (High Blood Pressure) 01/2021 - 09/2013
3	Cardiomegaly (Heart Hypertrophy) 01/2018 - 08/2014
2	Type 2 Diabetes Mellitus (MODY) 12/2023 - 01/2016
2	Inflammation (Inflammations) 01/2023 - 01/2020
2	Hypoxia (Hypoxemia) 01/2022 - 01/2016
2	COVID-19 01/2020 - 01/2020
2	Fibrosis (Cirrhosis) 01/2020 - 01/2020
2	Hypertrophy 01/2018 - 01/2017
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2023
1	Sepsis (Septicemia) 01/2023
1	Hypotension (Low Blood Pressure) 01/2023
1	Starvation 11/2022
1	Kidney Diseases (Kidney Disease) 01/2022
1	Essential Hypertension 01/2021
1	Breast Neoplasms (Breast Cancer) 01/2020
1	Glomerulonephritis 01/2020
1	Infections 01/2020
1	Cardiomyopathies (Cardiomyopathy) 01/2020
1	Neoplasms (Cancer) 01/2020
1	Tachycardia (Tachyarrhythmias) 01/2020
1	Myocardial Ischemia (Ischemic Heart Diseases) 01/2019
1	Long QT Syndrome 08/2015
1	Stroke (Strokes) 11/2014
1	Nephritis 08/2013
1	Cardiac Arrhythmias (Arrythmia) 08/2013
1	Obesity 01/2011
1	Maternal Obesity 01/2011
1	Torsades de Pointes (Torsade de Pointes) 03/2009

Drug/Important Bio-Agent (IBA)

5	phospholemmanIBA 01/2021 - 01/2004
5	Proteins (Proteins, Gene)FDA Link 01/2017 - 03/2002
4	Adenosine Triphosphatases (ATPase)IBA 01/2019 - 03/2003
3	Oxygen (Dioxygen)IBA 01/2020 - 01/2016
2	Fatty Acids (Saturated Fatty Acids)IBA 11/2022 - 01/2016
2	EnzymesIBA 01/2022 - 01/2004
2	SodiumIBA 12/2021 - 03/2003
2	TH 1177IBA 01/2020 - 08/2013
2	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 01/2019 - 09/2010
2	Antimycin AIBA 10/2006 - 10/2005
2	Cysteine (L-Cysteine)FDA Link 07/2005 - 08/2003
2	Biotin (Vitamin H)FDA Link 07/2005 - 08/2003
1	Sodium-Glucose Transport ProteinsIBA 12/2023
1	empagliflozinIBA 12/2023
1	KetonesIBA 10/2023
1	Sodium-Glucose Transporter 2 InhibitorsIBA 10/2023
1	DNA (Deoxyribonucleic Acid)IBA 01/2023
1	cyclic guanosine monophosphate-adenosine monophosphateIBA 01/2023
1	Cyclic GMP-Dependent Protein Kinases (Protein Kinase G)IBA 01/2023
1	Sirtuin 3IBA 11/2022
1	Protein Isoforms (Isoforms)IBA 01/2022
1	SaltsIBA 12/2021
1	NivolumabIBA 01/2020
1	CarbenoxoloneIBA 01/2020
1	CationsIBA 01/2020
1	CreatinineIBA 01/2020
1	Flecainide (Tambocor)FDA LinkGeneric 01/2020
1	Sodium Channels (Sodium Channel)IBA 01/2020
1	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 01/2020
1	Adenosine Monophosphate (AMP)IBA 01/2019
1	Sodium-Potassium-Exchanging ATPase (Sodium, Potassium ATPase)IBA 01/2019
1	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2019
1	Deoxyribonuclease I (Nickase)IBA 01/2019
1	Mitochondrial DNA (mtDNA)IBA 01/2019
1	Toll-Like Receptor 9IBA 01/2019
1	Adenosine Triphosphate (ATP)IBA 01/2018
1	Phosphoprotein Phosphatases (Phosphatases, Protein)IBA 01/2017
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2016
1	Glucose (Dextrose)FDA LinkGeneric 01/2016
1	GlycogenIBA 01/2016
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2016
1	Succinic Acid (Succinate)IBA 11/2014
1	Succinate Dehydrogenase (Fumarate Reductase)IBA 11/2014
1	Angiotensin IIIBA 08/2014
1	Interleukin-6 (Interleukin 6)IBA 08/2014
1	LeptinIBA 09/2013
1	Arginine (L-Arginine)FDA Link 08/2013
1	NG-Nitroarginine Methyl Ester (L-NAME)IBA 08/2013
1	T-Type Calcium Channels (T-Type Calcium Channel)IBA 08/2013
1	Dietary Fats (Dietary Fat)IBA 01/2011
1	Sildenafil Citrate (Viagra)FDA Link 09/2010
1	dofetilide (Tikosyn)FDA Link 03/2009
1	WortmanninIBA 01/2007
1	2- (2- amino- 3- methoxyphenyl)- 4H- 1- benzopyran- 4- oneIBA 01/2007
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 10/2006
1	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2006
1	Protein Kinases (Protein Kinase)IBA 10/2006
1	BuffersIBA 10/2006
1	NADPH Oxidases (NAD(P)H oxidase)IBA 12/2005
1	10,10'-dimethyl-9,9'-biacridinium (Lucigenin)IBA 12/2005
1	ChloridesIBA 12/2005
1	Adenosine (Adenocard)FDA LinkGeneric 12/2005
1	SB 203580IBA 10/2005
1	AntioxidantsIBA 07/2005

Therapy/Procedure

2	Therapeutics 10/2023 - 01/2020
1	Electrodes (Electrode) 01/2020
1	Vagus Nerve Stimulation 08/2015